serpin B10; bomapin; peptidase inhibitor 10; PI-10 (SERPINB10, PI10)

Function

• serine protease inhibitor
• may play a role in regulation of protease activities during hematopoiesis & apoptosis induced by TNF
• may regulate protease activities in the cytoplasm & in the nucleus

Structure

• belongs to the serpin family, Ov-serpin subfamily

Compartment

nucleus, cytoplasm

Expression

• expressed specifically in the bone marrow

More general terms

• serine protease inhibitor; serpin
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5273
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5273
• OMIM: https://mirror.omim.org/entry/602058
• UniProt: http://www.uniprot.org/uniprot/P48595.html