protein phosphatase-1 regulatory subunit 16B (TGF-beta-inhibited membrane-associated protein, hTIMAP, CAAX box protein TIMAP, ankyrin repeat domain protein 4)

Function

• may be a downstream target for TGF-beta1 signaling cascade in endothelial cells
• binds PP1 (probable)

Structure

contains 5 ANK repeats

Compartment

cell membrane; lipid-anchor (putative)

Expression

• highly expressed in vascular endothelium, CNS, lung, spleen, kidney & testis
• inhibited by TGF-beta1

More general terms

• protein phosphatase-1 regulatory subunit
• ankyrin repeat domain protein (ANKRD)

Database

• UniProt: http://www.uniprot.org/uniprot/Q96T49.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26051