protein phosphatase 1 regulatory subunit 14B; phospholipase C-beta-3 neighbouring gene protein (PPP1R14B, PLCB3N, PNG)

Function

• inhibitor of PPP1CA
• > 50-fold higher inhibitory activity when phosphorylated (putative)
• phosphorylated primarily on Thr-57 by PKC (in vitro)
• an unknown Ser is also phosphorylated by PKC (in vitro)

Structure

belongs to the PP1 inhibitor family

Compartment

cytoplasm (probable)

Expression

• ubiquitous
• expressed at low levels

More general terms

• protein phosphatase-1 regulatory subunit
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26472
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:100293
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26472
• OMIM: https://mirror.omim.org/entry/601140
• UniProt: http://www.uniprot.org/uniprot/Q96C90.html