protein phosphatase inhibitor 2; IPP-2 (PPP1R2, IPP2)

Function

• inhibitor of protein-phosphatase 1
• phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (putative)
• phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex
• heterodimer with PP1

Structure

• belongs to the protein phosphatase inhibitor 2 family

More general terms

• protein phosphatase-1 regulatory subunit

Additional terms

• protein phosphatase inhibitor 2-like protein (PPP1R2P)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5504
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5504
• OMIM: https://mirror.omim.org/entry/601792
• UniProt: http://www.uniprot.org/uniprot/P41236.html