bone morphogenetic protein 8B; BMP-8; BMP-8B; osteogenic protein 2; OP-2 (BMP8B, BMP8)

Function

• induces cartilage & bone formation
• may be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis
• role in Ca+2 regulation & bone homeostasis (putative)

Structure

• homodimer; disulfide-linked
• belongs to the TGF-beta family

Compartment

secreted

More general terms

• bone morphogenetic protein (BMP)
• TGF-beta family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=656
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:656
• OMIM: https://mirror.omim.org/entry/602284
• UniProt: http://www.uniprot.org/uniprot/P34820.html