fibroblast growth factor 22; FGF-22 (FGF22)

Function

• role in the fasting response, glucose homeostasis, lipolysis & lipogenesis
• can stimulate cell proliferation (in vitro)
• may be involved in hair development
• interacts with FGFR1 & FGFR2
• interacts with FGFBP1

Structure

• belongs to the heparin-binding growth factors family

Compartment

secreted (putative)

More general terms

• fibroblast growth factor

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=27006
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:27006
• OMIM: https://mirror.omim.org/entry/605831
• UniProt: http://www.uniprot.org/uniprot/Q9HCT0.html