leukocyte cell derived chemotaxin 1 (LECT1, chondromodulin-1, CHMI)

Function

• growth regulator
• stimulates the growth of cultured chondrocytes in presence of basic fibroblast growth factor
• inhibits the growth of cultured vascular endothelial cell
• replacement of cartilage by bone during endochondral bone development (putative)

Compartment

• cytoplasm, secreted protein
• inter-territorial matrix of cartilage

Expression

• cartilage specific

Pathology

weakly expressed in chondrosarcoma

More general terms

• leukocyte cell derived chemotaxin (lect)
• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/605147
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11061
• UniProt: http://www.uniprot.org/uniprot/O75829.html