CD52; CAMPATH-1 antigen; Cambridge pathology 1 antigen; epididymal secretory protein E5; CDw52 (CDW52, HE5)

Function

• may play a role in carrying & orienting carbohydrate, as well as having a more specific role

Compartment

cell membrane; lipid-anchor, GPI-anchor

Expression

• thymocytes
• lymphocytes
• monocytes/macrophages
• eosinophils
• epithelial cells lining male reproductive tract

Pathology

• expressed in most lymphoid malignancies

Pharmacology

• target of antitumor monoclonal antibody alemtuzumab (Campath-1H).

More general terms

• glypiated protein
• CD antigen

Database

• UniProt: http://www.uniprot.org/uniprot/P31358.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1043
• OMIM: https://mirror.omim.org/entry/114280
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1043