dehydrodolichyl diphosphate synthase (Dedol-PP synthase, DHDDS, HDS)

Function

• glycosylation pathway
• catalyzes cis-prenyl chain elongation to produce polyprenyl backbone of dolichol

Structure

• belongs to the UPP synthetase family

Alternative splicing

named isoforms=3

Expression

• expressed in testis & kidneys > heart, spleen, thymus

More general terms

• enzyme

Database

• OMIM: https://mirror.omim.org/entry/608172
• UniProt: http://www.uniprot.org/uniprot/Q86SQ9.html