actin-binding Rho-activating protein (striated muscle activator of Rho-dependent signaling, STARS, ABRA)

Function

• activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 & through a mechanism requiring Rho-actin signaling (putative)
• binds actin (putative)

Compartment

• localized to the I-band of the sarcomere & to a lesser extent to the sarcomeric structure between Z-lines (putative)

More general terms

• cytoskeletal protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N0Z2.html