talin-2 (TLN2, KIAA0320)

Function

• component of focal adhesion plaques
• links integrin to the actin cytoskeleton
• role in cell adhesion
• recruits PIP5K1C to focal adhesion plaques, activates its kinase activity

Structure

• contains 1 FERM domain
• contains 1 I/LWEQ domain

Compartment

cell junction, focal adhesion, synapse

More general terms

• cytoskeletal protein
• phosphoprotein

Additional terms

• talin-1 (TLN1, KIAA1027, TLN)

Database

• OMIM: https://mirror.omim.org/entry/607349
• UniProt: http://www.uniprot.org/uniprot/Q9Y4G6.html