ankycorbin (ankyrin repeat & coiled-coil structure-containing protein, retinoic acid-induced protein 14, novel retinal pigment epithelial cell protein, RAI14, KIAA1334, NORPEG)

Structure

• contains 7 ANK repeats

Compartment

• cytoplasm, cell cortex, cytoskeleton
• associated with cortical actin cytoskeleton in terminal web & cell-cell adhesion sites & stress fibers
• doesn't bind directly to F-actin

Alternative splicing

named isoforms=3

Expression

• expressed in placenta, muscle, kidney, testis > heart, brain, lung, liver , intestine
• isoform 2 is widely expressed & expressed in fetal & adult testes, & spermatozoa
• up-regulated by all-trans-retinoic acid in human retinal pigment epithelial cells

More general terms

• cytoskeletal protein
• retinoic acid-induced protein (RAI)

Database

• OMIM: https://mirror.omim.org/entry/606586
• UniProt: http://www.uniprot.org/uniprot/Q9P0K7.html