ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1, ARL11, ARLTS1)

Function

• role in apoptosis
• tumor suppressor (putative)

Structure

• belongs to the small GTPase superfamily, Arf family

Expression

• expressed in lung & leukocytes

Pathology

• defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL)

More general terms

• ADP-ribosylation factor-like protein (ARL)
• anti-oncoprotein (tumor suppressor protein)

Database

• OMIM: https://mirror.omim.org/entry/151400
• UniProt: http://www.uniprot.org/uniprot/Q969Q4.html