Shc proto-oncogene protein (Shc transforming protein)
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Function
conveys signal from src to ras
Expression
widely expressed protein
More general terms
More specific terms
- SHC-transforming protein 1; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1 (SHC1, SHC, SHCA)
- SHC-transforming protein 2; protein Sck; SHC-transforming protein B; Src homology 2 domain-containing-transforming protein C2; SH2 domain protein C2 (SHC2, SCK, SHCB)
- SHC-transforming protein 3; neuronal Shc; N-Shc; protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3 (SHC3, NSHC, SHCC)
References
- ↑ Rozakis-Adcock M et al Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature 360:689 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1465135
- ↑ Pawson T. Protein modules and signalling networks. Nature. 1995 Feb 16;373(6515):573-80. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7531822