cold shock domain-containing protein C2 (RNA-binding protein PIPPin, CSDC2, PIPPIN)

Function

• RNA-binding factor
• binds specifically to 3'-UTR ends of both histone H1 & histone H3.3 mRNAs, encompassing the polyadenylation signal
• role in negative regulation of histone variant synthesis in developing brain (putatitve)

Structure

• Contains 1 CSD domain (cold-shock domain)

Compartment

• nucleus, cytoplasm
• PIPPin-RNA complexes are located in the nucleus

More general terms

• RNA-binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y534.html