pumilio homolog 2 (pumilio-2, PUM2, KIAA0235, PUMH2)

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Function

Structure

  • homodimer
  • contains 8 pumilio repeats
  • the pumilio repeats mediate the association with RNA by packing together to form a right-handed superhelix that approximates a half donut
  • the number as well as the specific sequence of the pumilio repeats determine the specificity for target mRNAs
  • contains 1 PUM-HD domain

Compartment

cytoplasm

Alternative splicing

named isoforms=3

Expression

More general terms

References

Database