lymphocyte antigen 6 complex locus protein G6f (LY6G6F, C6orf21, G6F, NG32)

Function

• may play a role in the downstream signal transduction pathways involving GRB2 & GRB7
• interacts with GRB2 & GRB7 (phosphorylation-dependent)

Structure

• N-glycosylated
• homodimer; disulfide-linked
• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

plasma membrane; single-pass type 1 membrane protein

Alternative splicing

named isoforms=2

More general terms

• glycoprotein
• membrane protein
• phosphoprotein
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=259215
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:259215
• OMIM: https://mirror.omim.org/entry/611404
• UniProt: http://www.uniprot.org/uniprot/Q5SQ64.html