immunoglobulin superfamily member 3 (EWI-3) (IGSF3, KIAA0466)

Structure

• contains 8 Ig-like C2-type domain (immunoglobulin-like)

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

• expressed in a wide range of tissues
• high expression in placenta, kidney & lung Misc
• likely interchromosomal Alu-mediated fusion between IGSF3 on 1p13.1 & GGT on 22q11.2.
• breakpoints occurred inside Alu elements as well as in the 5' or 3' ends of them

More general terms

• glycoprotein
• membrane protein
• immunoglobulin superfamily protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3321
• OMIM: https://mirror.omim.org/entry/603491
• UniProt: http://www.uniprot.org/uniprot/O75054.html