protein reprimo (RPRM)

Function

• may be involved in the regulation of p53-dependent G2 arrest of the cell cycle
• seems to induce cell cycle arrest by inhibiting CDC2 activity & nuclear translocation of the CDC2 cyclin B1 complex (putative)

Structure

belongs to the reprimo family

Compartment

cytoplasm, membrane

Expression

induced by TP53/p53, following X-ray irradiation

Notes

'reprimo' signifies stop/repress

More general terms

• glycoprotein
• membrane protein

Additional terms

• reprimo-like protein (RPRML)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NS64.html