transmembrane protein 132A (HSPA5-binding protein 1, TMEM132A, HSPA5BP1, KIAA1583)

Function

• may play a role in embryonic & postnatal development of the brain
• increased resistance to cell death induced by serum starvation in cultured cells
• regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation (putative)
• interacts with HSPA5/GRP78 (putative)

Structure

belongs to the TMEM132 family

Compartment

• Golgi apparatus membrane
• endoplasmic reticulum membrane

Alternative splicing

named isoforms=4

More general terms

• membrane protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q24JP5.html