Torsin-1A-interacting protein 1 (TOR1AIP1)

Function

• binds to A- & B-type lamins
• role in membrane attachment & assembly of the nuclear lamina
• interacts with TOR1A
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the TOR1AIP family

Compartment

nucleus inner membrane

Alternative splicing

named isoforms=2

More general terms

• phosphoprotein
• nuclear protein
• membrane protein

Additional terms

• torsin-1A; dystonia 1 protein; torsin family 1 member A (TOR1A, DQ2, DYT1)

Database

• UniProt: http://www.uniprot.org/uniprot/Q5JTV8.html