Nodal modulator 2 (pM5 protein 2, NOMO2)

Function

• may antagonize Nodal signaling & subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN
• interacts with NCLN

Compartment

endoplasmic reticulum membrane

Alternative splicing

named isoforms=2

Expression

• expressed in pancreas & skeletal > heart

Genetics

• there are 3 copies of the NOMO gene on chromosome 16p12-p13: NOMO1, NOMO2 (AC Q5JPE7) & NOMO3 (AC P69849)
• all 3 very similar

More general terms

• glycoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q5JPE7.html