Nodal modulator 1 (pM5, NOMO1, PM5)

Function

• may antagonize Nodal signaling

Compartment

membrane

Expression

• expressed in colon tumor tissue & in adjacent normal colonic mucosa, 1.5-fold more in normal colonic mucosa than in colon tumor tissue (at protein level)

Genetics

• there are 3 copies of the NOMO gene on chromosome 16p12-p13: NOMO1, NOMO2 (AC Q5JPE7) and NOMO3 (AC P69849)
• all 3 very similar

More general terms

• glycoprotein
• membrane protein

Additional terms

• nodal homolog (NODAL)
• nodal modulator

Database

• UniProt: http://www.uniprot.org/uniprot/Q15155.html