protein transport protein Sec31B; SEC31-related protein B; SEC31B-1; SEC31-like 2 (SEC31B, SEC31L2)

Function

• component of coat protein complex II (COPII)
• may function in vesicle budding & cargo export from the endoplasmic reticulum
• interacts with SEC31A

Structure

• belongs to the WD repeat SEC31 family
• contains 7 WD repeats

Compartment

• cytoplasm, cytoplasmic vesicle, COPII-coated vesicle membrane peripheral membrane, cytoplasmic side, endoplasmic reticulum membrane

Alternative splicing

named isoforms=4

Expression

• ubiquitously expressed at low levels
• specific expression in thymus & testis
• expressed in testis by Sertoli cells, Leydig cells & spermatogonia
• expressed in cerebellum more prominently by Purkinje & granular cells (at protein level)

More general terms

• membrane protein
• WD repeat protein family

Component of

• COPII coat

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NQW1.html