RIMS-binding protein 2; RIM-BP2 (RIMBP2 KIAA0318 RBP2)

Function

• may play a role in the synaptic transmission
• interacts with RIMS1, RIMS2, CACNA1D & CACNA1B & potentially with other Ca+2 channel alpha-1 isoforms

Structure

• the SH3 domains mediate binding to a proline-rich motif in RIMS1, RIMS2, CACNA1D & CACNA1B (putative)
• belongs to the RIMBP family
• contains 3 fibronectin F3 modules contains 3 SH3 domains

Compartment

• cell membrane (putative)
• cell junction, synapse (putative)
• synaptic plasma membrane

Alternative splicing

named isoforms=3

More general terms

• membrane protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23504
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23504
• OMIM: https://mirror.omim.org/entry/611602
• UniProt: http://www.uniprot.org/uniprot/O15034.html