myelin & lymphocyte protein; T-lymphocyte maturation-associated protein (MAL)

Function

could be an important component in vesicular trafficking cycling between the Golgi complex & the apical plasma membrane could be involved in myelin biogenesis &/or myelin function lipoprotein

Structure

• belongs to the MAL family
• contains 1 MARVEL domain, amino acid residues 18-151, spanning all 4 transmembrane domains, the exoplasmic domains, & small segments of the N-terminal & C-terminal cytoplasmic domains

Compartment

membrane

Alternative splicing

named isoforms=4; A-D

Expression

• expressed in the intermediate & late stages of T-cell differentiation

More general terms

• lipoprotein
• transmembrane 4 protein

Database

• UniProt: http://www.uniprot.org/uniprot/P21145.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4118
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4118
• OMIM: https://mirror.omim.org/entry/188860