integrator complex subunit 2 (Int2, INTS2, KIAA1287)

Function

• component of the integrator complex
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the integrator subunit 2 family

Compartment

nucleus, membrane

Notes

• uncertain whether Met-1 or Met-9 is the initiator
• orthologous sequences (mouse & chicken) have shorter N-terminus

More general terms

• protein subunit
• membrane protein
• phosphoprotein

Component of

• integrator complex (multiprotein complex integrator)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H0H0.html