DAN domain family member 5 (cerberus-like protein 2, cerl- 2, Gremlin-3, cysteine knot superfamily 1, BMP antagonist 3) (DAND5 CER2 CKTSF1B3 GREM3 SP1)
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Function
- seems to play a role in the correct specification of the left-right axis
- may antagonize NODAL & BMP4 signaling
- cystine knot-containing proteins play important roles during development, organogenesis, tissue growth & differentiation (putative)
Structure
- belongs to the DAN family
- contains 1 CTCK (C-terminal cystine knot-like) domain
Compartment
secreted (probable)