dual oxidase maturation factor 1 (dual oxidase activator 1, Numb-interacting protein, DUOXA1, NIP, NUMBIP)

Function

• may be required for maturation & transport of DUOX1 from endoplasmic reticulum to plasma membrane
• may interact with NUMB

Structure

belongs to the DUOXA family

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

• specifically expressed in thyroid gland
• also detected in esophagus

More general terms

• transmembrane 5 protein
• glycoprotein
• chaperonin; chaperone

Additional terms

• dual oxidase maturation factor (DUOXA)

Database

• UniProt: http://www.uniprot.org/uniprot/Q1HG43.html