melanoma inhibitory activity protein 2 (MIA2)

Structure

• belongs to the MIA/OTOR family
• contains 1 SH3 domain

Compartment

secreted

Alternative splicing

named isoforms=2

Expression

• expressed in live > testis

Pathology

• role in the pathophysiology of liver disease
• may serve as a marker of liver damage
• expression higher in patients with severe cirrhosis or inflammation & chronic hepatitis

More general terms

• secreted protein
• glycoprotein

Additional terms

• melanoma
• melanoma-derived growth regulatory protein; melanoma inhibitory activity protein (MIA)

Database

• OMIM: https://mirror.omim.org/entry/608001
• UniProt: http://www.uniprot.org/uniprot/Q96PC5.html