solute carrier family 7 member 11; cystine/glutamate transporter; amino acid transport system xc-; Ca+2 channel blocker resistance protein CCBR1; xCT (SLC7A11)

Function

• Na+-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine & glutamate
• disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc (putative)

Structure

• belongs to the amino acid-polyamine-organocation (APC) superfamily, L-type amino acid transporter (LAT) (TC 2.A.3.8) family

Compartment

membrane

More general terms

• transmembrane 12 protein
• glycoprotein
• solute carrier family 7 (SLC7, SLC7A)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23657
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23657
• OMIM: https://mirror.omim.org/entry/607933
• UniProt: http://www.uniprot.org/uniprot/Q9UPY5.html