K+ voltage-gated channel subfamily F member 1; voltage-gated K+ channel subunit Kv5.1; kH1 (KCNF1)

Function

• putative voltage-gated K+ channel
• heteromultimer with KCNG3, KCNG4 & KCNV2
• interacts with DLG1

Structure

• the segment S4 is probably the voltage-sensor & is characterized by a series of positively charged amino acids at every third position
• belongs to the K+ channel family, F (TC 1.A.1.2) subfamily, Kv5.1/KCNF1 sub-subfamily

Compartment

membrane

Expression

• expressed in heart, brain, liver, skeletal muscle, kidney & pancreas

More general terms

• K+ channel subfamily F
• transmembrane 6 protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3754
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3754
• OMIM: https://mirror.omim.org/entry/603787
• UniProt: http://www.uniprot.org/uniprot/Q9H3M0.html