phosphatidylinositol N-acetylglucosaminyltransferase subunit Q; N-acetylglucosamyl transferase component GPI1; phosphatidylinositol-glycan biosynthesis class Q protein; PIG-Q (PIGQ GPI1)

Function

• part of the complex catalyzing transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the 1st step of GPI biosynthesis
• glycolipid biosynthesis; GPI-anchor biosynthesis
• associates with PIGA, PIGC, PIGH, PIGP & DPM2

Structure

belongs to the PIGQ family

Compartment

membrane (putative)

Alternative splicing

named isoforms=3

More general terms

• phosphatidylinositol-glycan biosynthesis protein (PIG-protein)
• transmembrane 5 protein
• glycoprotein

Component of

• UDP-N-acetylglucosamine phosphatidylinositol transferase (GPI-GlcNAc transferase, GPI-GnT)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9091
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9091
• OMIM: https://mirror.omim.org/entry/605754
• UniProt: http://www.uniprot.org/uniprot/Q9BRB3.html