phosphatidylinositol N-acetylglucosaminyltransferase subunit H; phosphatidylinositol-glycan biosynthesis class H protein; PIG-H (PIGH)

Function

• part of the complex catalyzing transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis
• glycolipid biosynthesis; GPI-anchor biosynthesis
• associates with PIGA, PIGC, PIGP, PIGQ & DPM2

Structure

belongs to the PIGH family

Compartment

cytoplasm

More general terms

• phosphatidylinositol-glycan biosynthesis protein (PIG-protein)
• phosphoprotein
• protein subunit

Additional terms

• phosphatidylinositol [PI] glycan

Component of

• UDP-N-acetylglucosamine phosphatidylinositol transferase (GPI-GlcNAc transferase, GPI-GnT)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5283
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5283
• OMIM: https://mirror.omim.org/entry/600154
• UniProt: http://www.uniprot.org/uniprot/Q14442.html