NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NK cell receptor E; killer cell lectin-like receptor C3 (KLRC3, NKG2E)

Function

• plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells & some cytotoxic T-cells
• can form disulfide-bonded heterodimer with CD94

Structure

contains 1 C-type lectin domain

Compartment

membrane

Alternative splicing

named isoforms=2; NKG2-E, NKG2-H

Expression

natural killer cells

More general terms

• killer cell lectin-like receptor C subfamily or NKG2 receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3823
• OMIM: https://mirror.omim.org/entry/602892
• UniProt: http://www.uniprot.org/uniprot/Q07444.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3823