solute carrier family 35 member B3; adenosine 3'-phospho 5'-phosphosulfate transporter 2; PAPS transporter 2; 3'-phosphoadenosine 5'-phosphosulfate transporter (SLC35B3, C6orf196, PAPST2, CGI-19)

Function

• mediates transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi
• compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon

Kinetic parameters: KM=2.2 uM for PAPS

Structure

• belongs to the nucleotide-sugar transporter family SLC35B subfamily

Compartment

Golgi membrane

Alternative splicing

named isoforms=3

Expression

preferentially & highly expressed in colon

More general terms

• solute carrier family 35
• transmembrane 10e protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H1N7.html