solute carrier family 6 member 12; Na+/Cl- betaine/GABA transporter; BGT-1 (SLC6A12)

Function

• transports betaine & GABA
• role in regulation of GABAergic transmission in brain via:
  • reuptake of GABA into presynaptic terminals
  • osmotic regulation
• interacts with LIN7C (putative)

Structure

• belongs to the Na+:neurotransmitter symporter (SNF) family

Compartment

membrane

Expression

• liver, heart, skeletal muscle, placenta
• widespread distribution in brain

More general terms

• solute carrier family 6
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/603080
• UniProt: http://www.uniprot.org/uniprot/P48065.html