inactive phospholipase C-like protein 1 (PLC-L1, phospholipase C-deleted in lung carcinoma, phospholipase C-related but catalytically inactive protein, PRIP, PLCL1)

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Function

Structure

  • contains 1 C2 domain
  • contains 1 PH domain
  • contains 1 PI-PLC X-box domain lacks the essential His at position 458 which is replaced by a Asn thus inactive (prediction)
  • contains 1 PI-PLC Y-box domain

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

Expression

  • expressed in a variety of fetal & adult organs including brain, lung & kidney
  • isoform 1 is predominantly expressed in brain

Pathology

More general terms

References

Database