Pre-mRNA-splicing factor ISY1 homolog (ISY1 KIAA1160)

Function

• role in pre-mRNA splicing (potential)
• identified in the spliceosome C complex
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the ISY1 family

Compartment

nucleus

Alternative splicing

named isoforms=3

More general terms

• splicing factor; snRNP-associated protein
• phosphoprotein

Component of

• spliceosome C complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q9ULR0.html