Kinetochore protein Nuf2 (hNuf2, hNuf2R, hsNuf2, cell division cycle-associated protein 1, NUF2, CDCA1, NUF2R)

Function

• component of kinetochore-associated NDC80 complex
• may interact with AURKB/Aurora-B
• can be phosphorylated by AURKA & AURKB

Structure

belongs to the NUF2 family

Compartment

• nucleus, kinetochore
• localizes to kinetochores from late prophase to anaphase
• localizes specifically to the outer plate of the kinetochore

More general terms

• cell division cycle-associated protein 4 (CDCA)
• kinetochore protein
• phosphoprotein

Component of

• NDC80 complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BZD4.html