leucine-rich repeat-containing protein 7 (protein LAP1, densin-180, LRRC7, KIAA1365, LAP1)

Function

• role in organization of synaptic cell-cell contacts
• interacts with CAMKII, CNKSR2 & DLG4
• interacts with CTNND2/Catenin delta-2
• forms a complex with N-cadherin through CTNND2

Structure

• belongs to the LAP (LRR & PDZ) protein family
• contains 18 LRR repeats (leucine-rich repeats)
• contains 1 PDZ domain (DHR domain)

Compartment

cytoplasm

Alternative splicing

named isoforms=3

Expression

• brain-specific
• isoform 3 is ubiquitously expressed

More general terms

• phosphoprotein
• leucine-rich repeat-containing protein (LRRC)

Database

• UniProt: http://www.uniprot.org/uniprot/Q96NW7.html