polyhomeotic-like protein 3 (hPH3, homolog of polyhomeotic 3, early development regulatory protein 3, PHC3, EDR3, PH3)

Function

• component of the Polycomb group PRC1 complex
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• contains 1 FCS-type zinc finger.
• contains 1 SAM domain (sterile alpha motif)

Compartment

nucleus

More general terms

• phosphoprotein
• zinc finger protein

Component of

• Polycomb group multiprotein PRC1 complex (PcG PRC1 complex, hPRC-H, PcG repressive complex 1)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NDX5.html