SAPS domain family member 1 (SAPS1, PPP6R1, KIAA1115)

Function

• role as regulatory subunit for PPP6C to promote dephosphorylation of NFKBIE & to oppose degradation of NFKBIE in response to TNF-alpha
• interacts with PPP6C & its substrate NFKBIE

Structure

belongs to the SAPS family

Compartment

cytoplasm

Expression

ubiquitous with higher expression in testis

More general terms

• phosphoprotein

Component of

• SAPS domain family member

Database

• UniProt: http://www.uniprot.org/uniprot/Q9UPN7.html