exportin-6 (Exp6, Ran-binding protein 20, XPO6, KIAA0370, RANBP20)

Function

• mediates nuclear export of actin & profilin-actin complexes in somatic cells
• found in a complex with XPO6, Ran, ACTB & PFN1.
• interacts with ACTB (RanGTP-dependent)

Structure

• belongs to the exportin family
• contains 1 importin N-terminal domain

Compartment

• nucleus, cytoplasm
• shuttles between nucleus & cytoplasm

More general terms

• phosphoprotein
• exportin

Database

• OMIM: https://mirror.omim.org/entry/608411
• UniProt: http://www.uniprot.org/uniprot/Q96QU8.html