transcriptional repressor p66 beta (p66/p68, GATA zinc finger domain-containing protein 2B, GATAD2B, KIAA1150)
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Function
- transcriptional repressor
- targets MBD3 to discrete loci in the nucleus
- binds the MeCP1 complex
- CR1 required for interaction with MBD3 & transcription repression.
- CR2 required for localization to discrete loci in nucleus
Structure
- contains 1 GATA-type zinc finger
Compartment
nucleus, in discrete foci