small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein, UBP, SGTA, SGT)

Function

• co-chaperone
• binds directly to HSC70 & HSP70 & regulates their ATPase activity

Structure

• contains 3 TPR repeats

Expression

ubiquitous

Pathology

• interacts with NS1 from parvovirus H-1, with Vpu & Gag from HIV-1

More general terms

• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/603419
• UniProt: http://www.uniprot.org/uniprot/O43765.html