actin-binding LIM protein 1; abLIM-1; actin-binding LIM protein family member 1; actin-binding double zinc finger protein; LIMAB1; Limatin (ABLIM1, ABLIM, KIAA0059, LIMAB1)

Function

• may act as scaffold protein
• may play a role in the development of the retina
• may play a role in axon guidance
• phosphorylated upon DNA damage, probably by ATM or ATR
• binds F-actin
• interacts with ABRA

Structure

• contains 1 HP (headpiece) domain
• contains 4 LIM Zn+2-binding domains

Compartment

• cytoplasm, cytoskeleton
• associated with the cytoskeleton (putative)

Alternative splicing

named isoforms=5

Expression

• detected in liver, heart, skeletal muscle, brain & retina
• in the retina, concentrated in the inner segment & in the outer plexiform layers

More general terms

• actin-binding LIM protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3983
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3983
• OMIM: https://mirror.omim.org/entry/602330
• UniProt: http://www.uniprot.org/uniprot/O14639.html