PHD finger protein 3 (PHF3, KIAA0244)

Function

• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• contains 1 PHD-type Zn+2 finger
• contains 1 TFIIS central domain

Alternative splicing

named isoforms=2

Expression

ubiquitous

Pathology

• expression is significantly diminished or absent in glioblastomas & astrocytomas

More general terms

• zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23469
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23469
• OMIM: https://mirror.omim.org/entry/607789
• UniProt: http://www.uniprot.org/uniprot/Q92576.html