kanadaptin (kidney anion exchanger adapter protein, solute carrier family 4 member 1 adapter protein, lung cancer oncogene 3 protein, SLC4A1AP, HLC3)

Function

• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

contains 1 FHA domain

Compartment

• nucleus, cytoplasm
• mainly nuclear
• small amounts are found in the cytoplasm

Expression

ubiquitously expressed

Notes

initially suggested a role in targeting SLC4A1 to the plasma membrane, but does not interact with SLC4A1 & has no effect on SLC4A1 trafficking

More general terms

• phosphoprotein
• nuclear protein
• solute carrier family 4 (SLC4, SLC4A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2295
• OMIM: https://mirror.omim.org/entry/602655
• UniProt: http://www.uniprot.org/uniprot/Q9BWU0.html