RNA polymerase 2 subunit RPB9 (RNA polymerase II p14.5 kD subunit, RPB14.5, RNA polymerase 2 subunit I, POLR2I, RPB9)

Function

• component of RNA polymerase 2
• POLR2I is part of the upper jaw surrounding the central large cleft & thought to grab the incoming DNA template
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
• contains 1 TFIIS-type Zn+2 finger

Compartment

nucleus (putative)

More general terms

• rna polymerase subunit
• nuclear protein
• phosphoprotein

Component of

• RNA polymerase-2

Database

• UniProt: http://www.uniprot.org/uniprot/P36954.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5438
• OMIM: https://mirror.omim.org/entry/180662